Projects
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Oligonucleotide fingerprinting of ribosomal RNA genes (OFRG) is a method that permits the identification of arrayed ribosomal RNA genes (rDNA)
through a series of hybridizaition experiments using small DNA probes. It provides a
cost effective means to extensively analyze microbial communities and should have
application in medicine, biotechnology and ecosystem studies. This project is funded
by NSF DBI.
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PRImer Selector (PRISE) is an interactive software package for PCR primer design. PRISE enables the design of sequence-specific / sequence-selective PCR primers. One important feature of PRISE is that it automates the task of placing primer-template mismatches at the 3' end of the primers - a property that is crucial for sequence selectivity / specificity.
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OligoSpawn is an efficient software for selecting two types of oligos,
namely unique and popular oligos, from large unigene databases.
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MSOAR is a high-throughput system for ortholog assignment on a genome scale.
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Two Sample Logo is a web-based application that calculates and visualizes
differences between two sets of aligned samples of amino acids or nucleotides.
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FLowgram Alignment Tool (FLAT) is a method for probabilistic matching of small RNA flowgrams against the reference genome.
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LRTag
is an efficient software tool for selecting a minimum set of TagSNPs
across multiple populations via the linkage disequilibrium criteria.
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MSTmap
is a genetic mapping tool which constructs the initial genetic map
from the minimum spanning tree (MST) of a graph. It is able to detect
genotyping errors and can handle various mapping populations including DH,
Hap, BC, and RIL.
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MergeMap
is software tool for merging individual genetic linkage maps into
a consensus map. When there are conflicts among the individual maps,
MergeMap is able to produce a graph which highlights the possible
problematic marker occurrences.
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